Retinyl Acetate

Goed

Antioxidant

Retinyl Acetate at a glance

  • Synthetic derivative of vitamin A, made from retinol and acetic acid
  • Converts to retinoic acid more slowly in skin
  • May offer some of the same benefits as retinol, but more research is needed
  • Seems to work well combined with other retinoids

Retinyl Acetate description

Retinyl acetate is a synthetic vitamin A derivative (chemically known as an ester) made from retinol and acetic acid. It is considered more stable than retinol; however, it also requires more conversion steps within skin to become retinoic acid. As such, retinyl acetate is not considered as effective as other retinoids such as retinyl propionate and retinal (also known as retinaldehyde). When encapsulated in a nanoparticle polymer delivery system, retinyl acetate’s delivery to skin was slower and showed better retainment after 24 hours (as measured on mouse skin). Given its slower conversion and taking a delivery system into account, in theory retinyl acetate may be less likely to provoke irritation in those sensitive to retinol. One study showed a product that contains the retinoids retinol, retinyl acetate, and retinyl palmitate at a combined concentration of 1.1% showed comparable improvements in signs of sun damage as 0.02% tretinoin, a prescription retinoid. Results were most notable on subjects with deep wrinkles after daily use for a period of 24 weeks. At the time of this writing, no published studies have looked at what results retinyl acetate on its own can provide. Usage levels of retinyl acetate in skin care range from 0.1–1%.

Retinyl Acetate references

  • Advances in Therapy, October 2022, pages 5,351–5,375
  • Advances in Dermatology and Allergology, August 2019, pages 392–397
  • Regulatory Pharmacology and Toxicology, March 2017, pages 102–104
  • International Journal of Pharmaceutics, February 2011, pages 281–288
  • Aesthetic Surgery Journal, August 2009, pages 74–77

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Beoordelingen van ingrediënten

Beste

Bewezen en ondersteund door onafhankelijk onderzoek. Uitstekend actief ingrediënt voor de meeste huidtypen of huidproblemen.

Goed

Noodzakelijk om de textuur, stabiliteit of doordringbaarheid van een formule te verbeteren.

Gemiddeld

Doorgaans niet-irriterend maar kan esthetische, stabiliteits- of andere problemen hebben die het nut ervan beperken.

Slecht

De kans op irritatie is aanwezig. Het risico wordt vergroot als het gecombineerd wordt met andere problematische ingrediënten.

Slechtste

Kan irritatie, ontsteking, droogheid, enz. veroorzaken. Kan in sommige gevallen voordelen bieden, maar over het algemeen is bewezen dat het meer kwaad dan goed doet.

onbekend

We konden dit niet vinden in onze Ingredient Dictionary. We registreren alle ontbrekende ingrediënten en werken ze regelmatig bij.

Geen beoordeling

We hebben dit ingrediënt nog niet beoordeeld omdat we het onderzoek ernaar nog niet hebben bekeken.