Palmitoyl Hexapeptide-12

Beste

Peptide

Palmitoyl Hexapeptide-12 at a glance

  • A synthetic peptide that matches a sequence of amino acids found in skin
  • Signals skin to look younger by boosting its firm feeling
  • Creates a supple surface by strengthening skin’s barrier
  • Requires a surprisingly low amount for efficacy

Palmitoyl Hexapeptide-12 description

Palmitoyl hexapeptide-12 is a lab-made peptide that blends the fatty acid palmitic acid with several amino acids, including glycine, histidine, and lysine. Combining this specifically engineered peptide with palmitic acid enhances its penetration into skin as well as the peptide’s stability. In the early days of peptides in skin care it went by the catchall term palmitoyl oligopeptide. The amino acid sequence of this peptide mimics that of peptides naturally occurring in skin, meaning skin recognises and can readily utilize it. It works on and within skin’s uppermost layers by influencing key supportive elements in skin that result in a firmer surface and minimized appearance of wrinkles. It also strengthens skin’s barrier by improving moisture retention, leaving skin feeling supple instead of rough. As a signal peptide, it can “tell” skin to look younger. It is considered safe as used in cosmetics, where its calculated efficacy is in the parts per million range. This translates to very low percentages used in skin care, as low as 0.0000001%; however, research is clear that small amounts of this peptide can produce impressive results. Palmitoyl hexapeptide-12 is most often used on its own rather than being part of a blend with other peptides, although such blends are available.

Palmitoyl Hexapeptide-12 references

  • Frontiers in Chemistry, October 2020, ePublication
  • International Journal of Toxicology, 2018, pages 90S-102S
  • Cosmetics, Volume 4, Issue 16, May 2017, pages 1–17
  • Tissue Engineering and Regenerative Medicine, February 2017, pages 73–80
  • Biomolecules and Therapeutics, July 2014, pages 321–327
  • International Journal of Cosmetic Science, June 2005, pages 155–160

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Beoordelingen van ingrediënten

Beste

Bewezen en ondersteund door onafhankelijk onderzoek. Uitstekend actief ingrediënt voor de meeste huidtypen of huidproblemen.

Goed

Noodzakelijk om de textuur, stabiliteit of doordringbaarheid van een formule te verbeteren.

Gemiddeld

Doorgaans niet-irriterend maar kan esthetische, stabiliteits- of andere problemen hebben die het nut ervan beperken.

Slecht

De kans op irritatie is aanwezig. Het risico wordt vergroot als het gecombineerd wordt met andere problematische ingrediënten.

Slechtste

Kan irritatie, ontsteking, droogheid, enz. veroorzaken. Kan in sommige gevallen voordelen bieden, maar over het algemeen is bewezen dat het meer kwaad dan goed doet.

onbekend

We konden dit niet vinden in onze Ingredient Dictionary. We registreren alle ontbrekende ingrediënten en werken ze regelmatig bij.

Geen beoordeling

We hebben dit ingrediënt nog niet beoordeeld omdat we het onderzoek ernaar nog niet hebben bekeken.