Palmitoyl Pentapeptide-4 Best Peptide Anti-Ageing Palmitoyl Pentapeptide-4 at a glance Synthetic signal peptide Boosts collagen and elastin Also helps regulate hyaluronic acid Ruled safe as used in cosmetics Palmitoyl Pentapeptide-4 description Trade name Matrixyl, a fatty acid mixed with amino acids. Manufactured by the French lab Sederma, it is used primarily as an ingredient in cosmetics making anti-wrinkle claims. Studies both from Sederma and from independent researchers have shown palmitoyl pentapeptide-4 can have an impact on the visual signs of ageing, including fine lines and wrinkles. Related ingredients: Peptides Palmitic Acid Amino Acids